Losec (omeprazole) is yet another medication we can add to the PPI classification (proton pump inhibitor) with its very own set of side effects.  Currently, Losec is only available by prescription and widely used in 10, 20 and 40 mg capsules, but also prescribed in 10 and 20 mg tablets.  Before taking Losec there is some interesting information you should know. 

History

Omeprazole was originally introduced to the acid reflux sufferers of the United States in 1988 by AstraZeneca using the brand name Losec.  In 1990 the FDA requested the name Losec be changed to Prilosec because of the overwhelming confusion with Losec and the diuretic Lasix.  Unfortunately, that didn’t fix the problem as Prilosec is often confused with the antidepressant Prozac.  Losec is still prescribed today under its original brand name. 

Indications

As a PPI, Losec decreases the amount of acid produced by your stomach.  Acid reflux symptoms occur when acid in the stomach cavity upward into the esophagus.  The stomach is equipped with a lining to protect itself from the erosive nature of the hydrochloric acid, however the esophagus is not.  Physicians will typically prescribe Losec for short term relief (4 to 8 weeks) of acid reflux symptoms relating to GERD, treatment for peptic and duodenal ulcers, as well as esophagitis.  It has also been used in conjunction with antibiotics in a triple therapy regimen for treatment of H. pylori.  The main reason for being prescribed a PPI classed drug is to minimize the amount of acid produced so the esophagus has time to heal.  Once this medication is stopped, your stomach goes back to normal acid production thus you may begin to experience symptoms again, and sometimes even worse than before.  Losec is not a cure for GERD and acid reflux related symptoms; it only offers temporary symptom relief.

Side Effects

Losec’s side effects are quite concerning, especially to a patient who is already dealing with stomach and esophageal pain.  Some of the more common “minor” side effects could include nausea, constipation, diarrhea, headache and skin rash.  The last thing a person with heartburn and indigestion wants is more stomach complaints.  Of the more serious side effects you should watch out for muscle pain and weakness, dizziness, sleep disturbance, mood alterations, fever and increased bruising.  Like with any medication, if you experience severe side effects or feel you cannot tolerate medication, immediately discontinue use and consult your physician. 

If you are currently taking any other prescription or over-the-counter medication, vitamin or herbal supplements, notify your physician prior to beginning Losec.  Your current regimen may lessen the effects of Losec, or even cause an exacerbation of side effects related to your other medicines.  NSAIDS (non-steroidal anti-inflammatory drugs) are a main cause for stomach ulcers, therefore discontinuation is important prior to treatment with Losec.  Steroids, like prednisone, have also been noted to cause acid reflux and other associated GERD symptoms.  A closer look at your current medical regimen may be indicated.